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Department of Genetics

 

Rafael Carazo Salas and colleagues have produced a special issue of Philosophical Transactions of the Royal Society B, available online on 23 September 2013, and in print in November. Papers in it are based on the recent Royal Society meeting entitled 'Cellular polarity : from mechanisms to disease'. They  cover current and forthcoming concepts such as asymmetry establishment, the role of feedback loops and mechanosensing and the importance of cell polarity establishment and re-establishment during cancer.  They also examine the role of innovative technologies and methodologies spreading in the field such as functional genomics, biophysical methods, mathematical modelling, computer simulations, organoids and disease models, quantitative and super-resolution microscopy and microfluidics.

Cellular polarity: From mechanisms to disease : http://rstb.royalsocietypublishing.org/site/2013/polarity.xhtml

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