Computational and Genomics Approaches to Drosophila Transcriptional Regulation
Boris Adryan - Group leader
Address: Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom
Email: ba255[at]cam.ac.uk
Tel.: +44 (0)1223 760209
Fax: +44 (0)1223 760241
Keywords
Drosophila, transcription factors, cis-regulatory modules, gene regulation, genomics, computational biology
Research interests
I have an interest in site-specific transcription factors (TFs) and their role in combinatorial gene regulation, particularly in Drosophila development. Gene activity is precisely regulated by TFs, which bind to regulatory bits of DNA forming so-called cis-regulatory modules (CRMs). These CRMs comprise defined combinations of binding sites for activating and repressing TFs. Although still enigmatic and challenging to access experimentally, I am interested in the characteristics of CRMs involved in metazoan development on the systems level. For more information see my group pages and my page at the Cambridge Systems Biology Centre .
Key publications
Please see information about my publications on the group website.
Page amended 2 Sep 2009