FlyBase : A Database of Drosophila Genes and Genomes
Nick Brown - Group Leader
Address : The Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, United Kingdom
Email: n.brown[at]gen.cam.ac.uk
Tel.: +44 (0)1223 334128
Fax: +44 (0)1223 334089
Boris Adryan - Scientific Advisor
Address : Cambridge Systems Biology Centre, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom
Email: ba255[at]cam.ac.uk
Tel.: +44 (0)1223 760209
Fax: +44 (0)1223 760241
Steven Marygold - Group Manager
Address: Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
Email: s.marygold[at]gen.cam.ac.uk
Tel.: +44 (0)1223 333170
Fax: +44 (0)1223 766732
Gillian Millburn - Senior Curator
Address: Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
Email: g.millburn[at]gen.cam.ac.uk
Tel.: +44 (0)1223 333963
Fax: +44 (0)1223 766732
Keywords
Drosophila, FlyBase, biocuration, ontologies
Research interests
FlyBase is the premier database of genetic, genomic and functional data for Drosophila species, with a focus on the model organism Drosophila melanogaster. FlyBase integrates information from the research literature and various external databases and projects, and makes these data available to the research community via our public website.
The FlyBase project is a collaboration between four groups based at Harvard University, USA (PI Bill Gelbart); Indiana University, USA (PIs Thom Kaufman and Kathy Matthews); The University of New Mexico, USA (PI Maggie Werner-Washburne); and The University of Cambridge, UK (PI Nick Brown).
The FlyBase-Cambridge division comprises a team of literature curators, ontologists and a software developer. Our primary task is to identify genetic data from scientific articles concerning Drosophila and to record these data in a systematic manner. Relevant data include all genetic entities (genes, alleles, transgenic constructs, etc.) and certain types of associated information such as phenotypes, genetic interactions and gene product functions. Curated data are subsequently integrated into the FlyBase database and website.
Other responsibilities of FlyBase-Cambridge include the production and maintenance of the FlyBase bibliography, and the development and maintenance of controlled vocabularies (ontologies) used in literature curation.
FlyBase-Cambridge staff give regular presentations and workshops within the University of Cambridge and around the UK, and we also attend the Annual Drosophila Research Conference in the USA and the European Drosophila Research Conference. We are also affiliated with the International Society for Biocuration.
Enquiries regarding FlyBase-Cambridge should be sent to the Group Manager, Steven Marygold. General enquires and feedback about FlyBase should be communicated using the 'Contact FlyBase' form.
4 key publications
- Fang R, Schindelman G, Van Auken K, Fernandes J, Chen W, Wang X, Davis P, Tuli MA, Marygold S, Millburn G, Matthews B, Zhang H, Brown N, Gelbart WM, Sternberg PW. (2012) Automatic categorization of diverse experimental information in the bioscience literature. BMC Bioinformatics. 13(1):16. [PMID: 22280404]
- McQuilton P, St Pierre SE, Thurmond J; FlyBase Consortium. (2012) FlyBase 101--the basics of navigating FlyBase. Nucleic Acids Res. 40(Database issue):D706-14. [PMID: 22127867]
- Rangarajan A, Schedl T, Yook K, Chan J, Haenel S, Otis L, Faelten S, DePellegrin-Connelly T, Isaacson R, Skrzypek MS, Marygold SJ, Stefancsik R, Cherry JM, Sternberg PW, Müller HM. (2011) Toward an interactive article: integrating journals and biological databases. BMC Bioinformatics 12:175. [PMID: 21595960]
- St Pierre S, McQuilton P (2009) Inside FlyBase: biocuration as a career. Fly 3(1):112-4. [PMID: 19182544]
Page updated 2 February 2012