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Jobs in the Department

Research Assistant/Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 09, 2019.

Applications are invited for a Postdoctoral Researcher to continue the work of a recently developed in vitro model system to study mammalian gastrulation and the role that mechanical forces play in this process. The work will be carried out in the laboratory of Professor Alfonso Martinez Arias in the Department of Genetics, University of Cambridge, Downing site in central Cambridge.

The work will suit a researcher who has postdoctoral experience in stem cell biology. Experience with mouse embryonic stem cells is essential and prior experience with organoids/gastruloids, desirable. The candidate must also have experience with transcriptomics (both sample preparation and data analysis).

Fixed-term: The funds for this post are available for 1 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please contact Alfonso Martinez Arias (ama11@cam.ac.uk) for further information about the project.

Please quote reference PC17844 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate

From Jobs at the University of Cambridge. Published on Dec 03, 2018.

We are looking to recruit a motivated postdoctoral researcher to work on the biochemical characterisation of a highly conserved non-canonical KRAB Zinc Finger Protein (KZFP) regulating mammalian epigenetic states within the research group of Anne Ferguson-Smith in the Department of Genetics.

The project involves the identification of protein partners and the role of protein subdomains in the targeted regulation of chromatin states by KZFPs. Mouse mutants and mutant ES cell models have been generated to underpin this project which will integrate in vivo functional analyses with proteomics and protein biochemistry.

Candidates should hold a PhD in biochemistry or molecular biology and should have experience in proteomics and bioinformatics, as well as mammalian cell culture.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Enquiries should be addressed to Professor Anne Ferguson-Smith (afsmith@gen.cam.ac.uk)

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Please quote reference PC17568 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Research Associate (Fixed Term)

From Jobs at the University of Cambridge. Published on Jan 11, 2019.

We are looking for a postdoctoral researcher to work on the development of an in vitro model system to study human gastrulation within the Research Group of Professor Alfonso Martinez Arias in the Department of Genetics.

The aim of the project is to extrapolate a novel Embryonic Stem Cell (ESC) based organoid system that we have developed in mouse to human ESCs, to enable the study of the early stages of post-implantation human development, in particular the process of gastrulation. The work builds on our finding that when a defined small number of mouse ESCs are aggregated in suspension and differentiated under controlled culture conditions, they undergo symmetry breaking, germ layer specification and patterned gene expression in a manner that mimics events in the embryo (see PMID: 25371360 and 28951435).

The work will suit a researcher who holds, or is about to be awarded, a PhD in molecular genetics or stem cell biology. Experience with human or mouse embryonic stem cells is essential and molecular biology, specifically with CRISPR/Cas9 desirable.

Please contact Professor Alfonso Martinez Arias (ama11@hermes.cam.ac.uk) for further information about the project.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Fixed-term: The funds for this post are available until 30 September 2021 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Please quote reference PC17878 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

University Lecturer in Statistical and Computational Modelling in Biology

From Jobs at the University of Cambridge. Published on Nov 19, 2018.

Applications are invited for a University Lectureship in Statistical and Computational Modelling in Biology based at the Department of Genetics.

The Department of Genetics is a world class research and teaching environment with particular strengths in genomics, population genetics and quantitative cell and developmental biology. We are searching for an outstanding scientist, with an excellent publication record, who is undertaking cutting edge and fundable work to complement our broad existing programme of research. In particular, we are encouraging applicants who will strengthen our current research activities in the area of quantitative genetics taking approaches that include mathematics, modelling, computing, bioinformatics and statistics. (http://www.gen.cam.ac.uk/research-groups/research-by-subject).

The candidate should also have an aptitude and enthusiasm for teaching at undergraduate and graduate level, and will be expected to contribute to these activities in the Department. This will include the design and delivery of undergraduate and graduate-level lecture courses and in particular the new undergraduate course in Statistical, Computational and Mathematical Modelling in Biology The successful candidate will also be expected to perform related academic duties associated with examinations and other forms of assessment.

We welcome applications from individuals with degrees in the biological, mathematical or physical sciences who are focused on applying their expertise to research in relevant areas of modern genetics. Applicants should also be able to demonstrate an effective contribution to teaching, and more general contributions to their subject and to related activities, for example to the public understanding of science.

Prospective candidates are invited to contact the Head of Department, Professor Anne Ferguson Smith, for informal enquires (Tel: +44 (0) 1223 339984, e-mail: afsmith@gen.cam.ac.uk).

The Department is committed to the Athena SWAN scheme to provide equal opportunities and to advance the representation of women in science. We welcome applications from all qualified candidates irrespective of gender but, as women are currently under-represented at this level in our department, we strongly encourage applications from female candidates. Appointment will be based on merit alone. The Department strongly supports DORA (https://sfdora.org) and will assess research on its own merits rather than on the basis of the journal in which it is published.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload the following application documentation - Curriculum Vitae (CV), a full publications list, highlighting up to 5 publications you regard as most significant, and a statement of professional, teaching and research experience and a description of your future research plans.

If you upload any additional documents to those above, we will not be able to consider these as part of your application.

Short-listed candidates will be invited to visit the Department, give a research seminar and short teaching talk, and attend a formal interview. This process will take place during March 2019.

Please quote reference PC17441 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.