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Departmental Seminar - Gislene Pereira : Coordination of spindle positioning and cell cycle progression in yeast

When May 04, 2017
from 02:00 PM to 03:00 PM
Where Biffen Lecture Theatre, underneath Dept of Genetics
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4th May 2017
Title: Coordination of spindle positioning and cell cycle progression in yeast.
Dr. Gislene Pereira, German Cancer Research Center, Heidelberg
Abstract:
The positioning of the mitotic spindle along the mother-daughter cell polarity axis is critical for the outcome of cell division in asymmetrically dividing budding yeast cells. A surveillance mechanism, known as the spindle position checkpoint (SPOC), senses defects in spindle orientation thereby inhibiting mitotic exit and cytokinesis. I will discuss our currently understanding of SPOC activation and how temporal and compartment-specific regulatory networks determine mitotic exit in this system.

Host: Marco Geymonat