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Dr Avazeh Ghanbarian

Dr Avazeh Ghanbarian

Postdoc - Bioinformatician

Regulation of Transcription and Translation

Avazeh Ghanbarian is available for consultancy.


Biography:

Research Associate (2015-Now)
Department of Genetics, University of Cambridge, Cambridge, UK
Research Topic: Dynamics of Translation in stem cells prior/post differentiation
PhD in Biology (2012-2015)
University of Bath, Bath, UK
Thesis Topic: Evolution of Gene Expression
Master of research in Bioinformatics and Computational Biology (2007-2008)
University of Leeds, Leeds, UK
Thesis Topic: Inter-Species Network Visualisation, IntAct, EBI
Master’s degree in Computer Science (2002-2005)
Tehran, Iran
Thesis Topic: Color Reduction Based on Ant Colony
Bachelor’s degree in Computer Science (1997-2001)
Tehran, Iran
Thesis Topic: Finding the optimum path for players in Robocup coach competition based on ant colony optimization

 

Research Interests

Regulation of Transcription and Translation
Evolution of Gene Expression
Epigenetics
Statistical Genomics
Pattern Recognition

Teaching

Undergraduate Supervision
Bioinformatics course, University of Cambridge, Cambridge, UK
Teaching Bioinformatics, R and Unix
Bioinformatics Training Center, University of Cambridge, Cambridge, UK
Statistics and Bioinformatics demonstrator
University of Bath, Bath, UK
IT demonstrator
University of Leeds, Leeds, UK

Key Publications

Ghanbarian, A.T. and Hurst, L.D., Neighboring genes show correlated evolution in gene expression, Molecular Biology and Evolution, 32 (7), 1748-1766, 2015.
Laurence D Hurst, Avazeh T Ghanbarian, Alistair RR Forrest, Lukasz Huminiecki, The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome, PLoS Biology, Vol 13, Issue12, e1002315, 2015
Schueler, A.*, Ghanbarian, A.T.* and Hurst, L.D., Purifying selection on splice-related motifs, not expression level nor RNA folding, explains nearly all constraint on human lincRNAs, Molecular Biology and Evolution, 31 (12), 3164-3183, 2014.
* Joint first authorship
Jichang Wang, Gangcai Xie, Manvendra Singh,  Avazeh T. Ghanbarian, Tamás Raskó, Attila Szvetnik, Huiqiang Cai, Daniel Besser, Alessandro Prigione, Nina V. Fuchs, Gerald G. Schumann, Wei Chen, Matthew C. Lorincz, Zoltán Ivics, Laurence D. Hurst, Zsuzsanna Izsvák, Primate-specific endogenous retrovirus driven transcription defines naïve-like stem cells, Nature, 516 (7531), 405-409, 2014.
Tashakkori Ghanbarian, A., Kabir, E. and Moghadam, N., Color Reduction Based on Ant Colony, Pattern Recognition Letters (Elsevier), Vol. 28, Issue 12, pp. 1383–1390, 2007.
Tashakkori Ghanbarian, A., Kabir, E., An Ant-based Approach to Color Reduction, Ant Colony Optimization and Swarm Intelligence, 5th International Workshop, ANTS 2006 Conf., LNCS 4150.

Selected other publications:
Oliver SP Davis, Gavin Band, Matti Pirinen, Claire MA Haworth, Emma L Meaburn, Yulia Kovas, et al, The correlation between reading and mathematics ability at age twelve has a substantial genetic component, Nature communications 5, p. 4204, 2014
P Holmans, V Moskvina, L Jones, M Sharma, The International Parkinson's Disease Genomics Consortium (IPDGC), et al, A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease, Human molecular genetics, 22 (5), 1039-1049, 2013.
The Esophageal Adenocarcinoma Genetics Consortium, The Wellcome Trust Case Control Consortium 2, et al, Common variants at the MHC locus and at chromosome 16q24. 1 predispose to Barrett's esophagus, Nature Genetics 44 (10), 1131-1136, 2012.
B. Aranda, P. Achuthan, Y. Alam-Faruque, I. Armean, A. Bridge, C. Derow, M. Feuermann, A. T. Ghanbarian, et al, The IntAct molecular interaction database in 2010, Nucleic Acids Research, Vol. 38, Database issue D525-D531, 2010.