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Department of Genetics

Human evolutionary genetics


Research in computational genetics; human and primate evolution.

Postdoc funding opportunities available for recently-qualified or final-year PhDs in computer science, physics, engineering  or mathematics.


Key publications: 
  • Skov, L, et al. ‘Detecting archaic introgression using an unadmixed outgroup’. PLoS Genetics, 14(9), e1007641 (2018)
  • Scally, A. ‘High-quality genomes reveal new differences between the great apes’. Nature 559.7714: 336 (2018)
  • Scerri, E, …, A Scally, L Chiki, ‘Did our species evolve in subdivided populations across Africa, and why does it matter?’, Trends in Ecology and Evolution, 33(8), 582–594 (2018)
  • Scheib, C et al. ‘Ancient human parallel lineages within North America contributed to a coastal expansion’, Science 360, 1024–1027 (2018)
  • Scally, A, ‘Global clues to the origins of human germline mutation’, eLife 2017;6:e27605 (2017)
  • Nater, A et al., ‘Morphometric, behavioral, and genomic evidence for a new orangutan species’, Current Biology, 27, 1–12, (2017)
  • Narasimhan, VM, R Rahbari, A Scally et al., ‘Estimating the human mutation rate from autozygous segments reveals population differences in human mutational processes’ Nature Communications 8 (2017)
  • Seoighe, C, A Scally, ‘Inference of candidate germline mutation rate polymorphisms in human from genome-wide haplotype data’, PLoS Genetics 13(1): e1006549. (2017)
  • de Manuel, M et al., ‘Chimpanzee genome sequencing reveals population structure and ancient admixture with bonobos in the wild’, Science, 354.6311, 477-481 (2016)
  • Scally, A, ‘The mutation rate in human evolution and demographic inference’, Current Opinion in Genetics and Development, doi: 10.1016/j.gde.2016.07.008 (2016)
  • Scally, A, ‘Mutation rates and the evolution of germline structure’, Phil. Trans. Royal Soc. B, 371, 20150137 (2016)
  • Groucutt, HS, ... , A Scally, ‘Rethinking the dispersal of Homo sapiens out of Africa’, Evolutionary Anthropology 24(4), 149-164 (2015)
  • Xue, Y, J Prado-Martinez, PH Sudmant, V Narasimhan, ... , A Scally, ‘Mountain gorilla genomes reveal the impact of long-term population decline and inbreeding’, Science, 348, 242–245 (2015)
  • Pagani, L et al., ‘Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians’, The American Journal of Human Genetics 96(6), 986-991 (2015)
  • Scally, A, et al. ‘A genome-wide survey of genetic variation in gorillas using reduced representation sequencing’, PLoS ONE 8(6), e65066 (2013)
  • Mailund, T et al. ‘A new isolation with migration model along complete genomes infers very different divergence processes among closely related great ape species’, PLoS Genetics 812, e1003125 (2012)
  • Scally, A, R Durbin, ‘Revising the human mutation rate: implications for understanding human evolution’, Nature Reviews Genetics (2012)
  • Scally, A et al., ‘Insights into hominid evolution from the gorilla genome sequence’, Nature 483, 169–175 (2012)
  • 1000 Genomes Project Consortium, ‘An integrated map of genetic variation from 1,092 human genomes’, Nature 491, 56–65 (2012)
  • Mills, RE et al. ‘Mapping copy number variation by population-scale genome sequencing’, Nature 470, 59-65 (2011)
  • Quail, MA et al. ‘A large genome centre's improvements to the Illumina sequencing system’, Nature Methods 5, 1005-1010 (2008)
  • Bentley, DS et al., ‘Accurate whole human genome sequencing using reversible terminator chemistry’, Nature 456, 53-59 (2008)
Group Leader : Scally Group
Dr Aylwyn  Scally

Contact Details

Department of Genetics,
University of Cambridge,
Downing Street,
Cambridge CB2 3EH,
United Kingdom
+44 (0)1223 766931
Takes PhD students
Not available for consultancy