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Department of Genetics

 
Joseph Baxter microscope 590

Projects

The Genetics Department offers the choice of “wet” or “dry” projects, which are undertaken in the Lent Term.

Examples of project titles offered from recent previous years

  • Investigating the mechanisms of pattern regulation in the zebrafish tailbud
  • Signalling mechanisms controlling petal patterning
  • Generation of mutant mouse ESCs to investigate mechanisms controlling
  • Modelling the demographic and selective processes shaping diversification of a crater lake cichlid fish
  • Regulation of transposon alternative splicing in the soma and germline
  • Is Topoisomerase 2 alpha required to maintain mitotic chromosome
  • Dynamics of TRIM28 activity upon rapid depletion
  • Lactobacillus versus E. coli
  • Diet-induced alterations of skeletal morphology in an East African cichlid: Intersections of epigenetics and phenotypic plasticity
  • Exploring population genetic spatial processes
  • Characterising plant molecular compasses and their role(s) in petal pattern
  • Exploration and bioinformatics analysis of disease comorbidities
  • Demographic history of diverse species from whole genome sequences
  • mRNA decay and the control of germline stem cell differentiation
  • Integrating ancient African Y-chromosome lineages into present-day phylogenies. 
  • Topoisomerase II depletion by the auxin-inducible degron system in human cells.
  • Mammalian epigenetic control: chromosome architecture and topology in vivo – new insights from genomic imprinting.
  • Dissecting Ras inhibition by a novel class of Ras-interacting proteins - a synthetic approach.
  • CRISPR-mediated deletion of transposable elements.
  • How does an innate immune system recognize a pathogen that is very similar to the host?
  • Mechanisms regulating genomic stability during germline development.
  • Examine the role of polymerase gamma(tam) in mitochondrial DNA replication and elimination.
  • Functional circuitry of odour discrimination in Drosophila larvae.
  • Comparative analysis of cancer gene expression data.
  • Genetic basis of bullseye pattern formation in Hibiscus flowers.
  • Screening for genes that regulate axonal endoplasmic reticulum structure.
  • Analysing single cell learning and behaviour with machine learning approaches.
  • Drosophila nicotinic acetylcholine receptors.
  • Exploring population turnover using evolutionary genetic simulation.
  • Systems-level quantitative analyses of spindle pole asymmetric fate.
  • The role of centrosome anchoring and release in Drosophila dorsal-ventral axis formation.
  • A New Approach to the Treatment of UTIs.
  • Why does life history predict genomic diversity?