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Departmental seminar - Julius Brenneke : Hacking the Gene Expression Machinery for Genome Defence

When Oct 25, 2018
from 02:00 PM to 03:00 PM
Where Biffen Lecture Theatre, underneath Dept of Genetics
Contact Name Felipe Karam Teixeira
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The Genetics Seminar Series talk will be at 14:00 in the Biffen Lecture Theatre on Thursday 25th October 2018.  There will also be an opportunity to meet the speaker in the Department of Genetics tea room immediately after the talk from 15:00 until 15:30 and biscuits will be provided. 

Dr Julius Brennecke from IMBA, Vienna BioCenter will be speaking and the title of the talk is,

''Hacking the gene expression machinery for genome defense''

Abstract:
There is an ongoing arms race between mobile genetic elements such as transposons and host genome defense systems. Both, prokaryotes and eukaryotes rely on small RNA pathways for the sequences specific silencing of transposons and other invading nucleic acids: CRISPR/Cas systems in bacteria and RNA interference pathways in plants, fungi, and animals. I will give a conceptual overview of the molecular logic of the Piwi/piRNA pathway, the major transposon silencing system in the animal germline. The focus of my talk will be on the intersection of the piRNA pathway with heterochromatin biology, and how evolution found ways to bypass the canonical ways of gene expression.

Host: Felipe Karam Teixeira