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Departmental Seminar - Jon Clarke : Directing and shaping the inside-out axis of the vertebrate brain

When Oct 20, 2016
from 02:00 PM to 03:00 PM
Where Biffen Lecture Theatre, underneath Dept of Genetics
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The next Genetics Seminar Series talk will be at 14:00 in the Biffen Lecture Theatre on Thursday 20th October 2016.  There will also be an opportunity to meet the speaker in the tea room immediately after the talk from 15:00 until 15:30 and fruit and snacks will be provided.

Professor Jon Clarke from Department of Developmental Neurobiology, King's College London will be speaking and the title of the talk is,

''Directing and shaping the inside-out axis of the vertebrate brain''

We are attempting to understand the developmental mechanisms that drive organ and cell morphogenesis in the vertebrate embryo central nervous system. The fundamental building block of the embryonic vertebrate brain is the neural tube which is an epithelium composed of apicobasally polarized neural progenitors. The polarity of these cells is essential for many of the key events in building a brain but how this polarity is established is poorly understood. We use the accessibility and transparency of the zebrafish embryo to better understand neuroepithelial polarity and morphogenesis, and we are currently focused on  the role of cell division-dependent and division-independent processes, directional signals from the ECM and the potential role of biomechanical forces.

Host: Ben Steventon