THE TALK HAS BEEN CANCELLED [as of 11 Feb]
The Genetics Seminar Series talk will be at 14:00 in the Part II Room on Thursday 14th February. There will also be an opportunity to meet the speaker in the Department of Genetics tea room immediately after the talk from 15:00 until 15:30 and biscuits will be provided.
Professor Molly Przeworski from Columbia University, New York will be speaking and the title of the talk is,
''An evolutionary perspective on meiotic recombination in vertebrates''
Abstract:
Meiotic recombination is a fundamental genetic process that generates new combinations of alleles on which natural selection can act and ensures the proper alignment and segregation of chromosomes. Recombination events are initiated by double strand breaks deliberately inflicted on the genome during meiosis. As I will discuss, in vertebrates, there appear to be two main mechanisms by which the locations of these double strand breaks are specified: through binding of the gene PRDM9 or by localization to promoter-like features of the genome. I will present our recent work linking these two mechanisms to dramatic differences in the evolutionary dynamics of recombination hotspots, and draw out potential implications for hybridization between closely related species.
Host: Richard Durbin
Graduate students are expected to attend unless they have made alternative arrangements with the series organisers.