Biography
Tamsin grew up in Singapore and moved to the UK for her undergraduate degree in Biochemistry at the University of Cambridge. She completed her DPhil at the University of Oxford under the supervision of Professor Ilan Davis, studying the regulation of neural stem cells in the fruit fly larva. In 2020, Tamsin joined the group of Dr Felipe Karam Teixeira in the Department of Genetics using the model system of the fruit fly germline. As a Herchel Smith Postdoctoral Fellow, Tamsin will use single molecule imaging of RNA molecules in the fruit fly ovary to examine the molecular regulation of rapid fate transitions during stem cell differentiation. Outside the lab, Tamsin enjoys running and baking.
Publications
Gui J*, Samuels TJ*, Grobicki KZA, Teixeira FK (2023) Simultaneous activation of Tor and suppression of ribosome biogenesis by TRIM-NHL proteins promotes terminal differentiation. Cell Reports https://doi.org/10.1016/j.celrep.2023.112181
Samuels TJ, Järvelin AI, Ish-Horowicz D, Davis I (2020) Imp/IGF2BP levels modulate individual neural stem cell growth and division through myc mRNA stability. eLife https://doi.org/10.7554/eLife.51529
Samuels TJ, Arava Y, Järvelin AI, Robertson F, Lee JY, Yang L, Yang CP, Lee T, Ish-Horowicz D, Davis I (2020) Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation. Biology Open, https://doi.org/10.1242/bio.049684
Hailstone M, Waithe D, Samuels TJ, Yang L, Costello I, Arava Y, Robertson EJ, Parton RM, Davis I (2020) CytoCensus: mapping cell identity and division in tissues and organs using machine learning. eLife, https://doi.org/10.7554/eLife.51085
Yang CP, Samuels TJ, Huang Y, Yang L, Ish-Horowicz D, Davis I, Lee T (2017) Imp and Syp RNA binding proteins govern decommissioning of Drosophila neural stem cells. Development 144, 3454-3464 https://doi.org/10.1242/dev.149500
* these authors contributed equally
