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Department of Genetics

 

EDUCATION

2017-2022 P.h.D Degree, University Of Cambridge (United Kingdom), Department of Genetics, Cahir O’KANE Lab

2013-2016- Master's Degree, Istanbul Technical University, (Turkey), Department of Molecular Biology And Genetics, Eda Tahir TURANLI Lab

2012 (6 Months), ERASMUS Exchange, University Of Roskilde, (Denmark), Department of Molecular Biology

2008-2012- BSc Degree, ISTANBUL University, (Turkey), Faculty of Sciences-Department of Molecular Biology & Genetics

PROJECTS-Past and present

2017- PhD Project— Role of Hereditary Spastic Paraplegia (HSP) Proteins in Organization of Axonal Endoplasmic Reticulum (ER) and ER-mitochondria Contacts in Drosophila

2013-2016-Master Project—Investigation of Notch Signalling Pathway Proteins as Potential Biomarkers for Differentiating Multiple Sclerosis Clinical Subtypes

2013-2015-Research Project— Investigation of antioxidant, anti-cancer, and antimicrobial effects of Eremurus spectabilis' extracts on Human PC-3 cell line.

2013-2015-Research Project— Investigation of Bing l's Propolis effects against the oxidative stress induced by homocysteine in human brain microvascular endothelial cells.

2012-2012-Bachelor’s Project—Identification of miR-29a targets in mitochondrial DNA. https://www.researchgate.net/publication/270882489_Identification_of_miR- 29a_targets_in_mitochondrial_DNA

PUBLICATIONS

Öztürk Z, O’Kane CJ and P rez-Moreno JJ (2020) Axonal Endoplasmic Reticulum Dynamics and Its Roles in Neurodegeneration. Front. Neurosci. 14:48. doi: 10.3389/fnins.2020.00048

Zeynep Tuzcu, Gulden Koclar, Can Ali Agca, Gurkan Aykutoglu, Gokhan Dervisoglu, Musa Tartik, Ekrem Darendelioglu, Zeynep  öztürk, Bulent Kaya, Kazim Sahin, Antioxidant, antimicrobial and anticancer effects of different extracts from wild edible plant eremurus spectabilis leaves and roots. Int J Clin Exp Med 2017;10(3):4787-4797

JOB EXPERIENCE and SHORT TERM VISITS

Part Time Research Assistant-Department of Genetics, University of Cambridge, UK-O’Kane Lab, 01.12.202-Present

Teaching and Mentoring-Genetics, Genome editing, Mentoring in silico projects on genetic variants pathogenecity, https://www.horizoninspires.com/instructors, 16/07/2020-Present

Teaching-Biotechnology and Genetics Course, Neuroscience Course, Oxford Summer Courses- https://oxfordsummercourses.com (UK),01/07/2019-01/09/2021

Research Assistant- Bingol University-Department of Molecular Biology and Genetics- Turkey,17/04/2013-07/04/2017

Summer visit, University of Cambridge, Department of Genetics, UK, 11/07/2011-20/09/2011

Summer visit , TUBITAK (The Scientific and Technological Research Council of Turkey) Gene Engineering Institute,–Molecular biology Lab,Kocaeli, Turkey,09/08/2010-10/09/2010

Summer visit, The Hospital of Memorial-In Vitro Fertilization (IVF) Lab, Istanbul,Turkey,01/07/2010-20/08/2010

Biography

EDUCATION

2017- - P.h.D Degree, University Of Cambridge (United Kingdom), Department of Genetics, Cahir O’KANE Lab

2013-2016- Master's Degree, Istanbul Technical University, (Turkey), Department of Molecular Biology And Genetics, Eda Tahir TURANLI Lab

2012 (6 Months), ERASMUS Exchange, University Of Roskilde, (Denmark), Department of Molecular Biology

2008-2012- BSc Degree, ISTANBUL University, (Turkey), Faculty of Sciences-Department of Molecular Biology & Genetics

 

Research

Organele biology in health and disease, contact sites of organelles, ER-mitochondria contacts, mitochondria, human Genetics, Neurodegenerative diseases, Drosophila Genetics, Cell Biology, Neuron Biology, Molecular Mechanisms of Neurodegeneration, CRISPR/Cas9 Gene Editing

Publications

Key publications: 

Öztürk Z, O’Kane CJ and Pérez-Moreno JJ (2020) Axonal Endoplasmic Reticulum Dynamics and Its Roles in Neurodegeneration. Front. Neurosci. 14:48. doi: 10.3389/fnins.2020.00048  https://www.frontiersin.org/articles/10.3389/fnins.2020.00048/full

Other publications: 

Zeynep Tuzcu, Gulden Koclar, Can Ali Agca, Gurkan Aykutoglu, Gokhan Dervisoglu, Musa Tartik, Ekrem Darendelioglu, Zeynep  öztürk, Bulent Kaya, Kazim Sahin, Antioxidant, antimicrobial and anticancer effects of different extracts from wild edible plant eremurus spectabilis leaves and roots. Int J Clin Exp Med 2017;10(3):4787-4797

Teaching and Supervisions

Teaching: 

16/07/2020-Present-Teaching and Mentoring-Genetics, Genome editing, Mentoring in silico projects on genetic variants pathogenecity, https://www.horizoninspires.com/instructors

01/07/2019-01/09/2021-Teaching-Biotechnology and Genetics Course, Neuroscience Course, Oxford Summer Courses- https://oxfordsummercourses.com (UK)

17/04/2013-07/04/2017-Research Assistant- Bing l University-Department of Molecular Biology and Genetics- Turkey

Other Professional Activities

President and Founder of Cambridge University Turkish Society, 2019-Present

CamBrain Organization Committee, 2020-2021

The Cambridge Union Member, https://www.cus.org, Life long

May Week Alternative Ambassador, https://www.facebook.com/mayweekalternative/, 2019-2020

Interfaith Student Leader and alumni in Campus by CCJ, http://www.ccj.org.uk, Life Long

Graduate student : O'Kane Group
Research Assistant-Part Time-O'Kane Lab
Areas of Interest: 
"Organization and Function of Axonal ER"
Neurodegeneration, Neurodegenerative diseases, Neuron Biology, Drosophila Genetics, Genome editing tools, Organelle biology
Email address: 
Cahir O’Kane Group
Department of Genetics
University of Cambridge
Downing Street
Cambridge, UK
CB2 3EH

Affiliations